Does an Azure backup of a virtual machine remove users from the system when running?

I have not found any documentation on this yet and I wish to learn from the experience of others here. A standard 1TB SSD is connected to my Windows 2019 virtual machine as a LUN 0 data disk and would like to know if the Azure Backup policy I just created would last for a long time and if this would cause connectivity issues for our RDP. users while running. I imagine that I will eventually discover it, but I'm just trying to warn my users if we know that this causes connectivity issues.