Web Hosting – Add Cron with ISPmanager

I have a website, let's call it username53282.hosting.com. I do not know how to create a Cron job. I used this command to create

/ usr / bin / php ~ / user53282.hosting.com / 1 / script.php

I think the order is wrong. I receive this in my email. Can not open the input file: /var/www/user53282/data/user53282.hosting.com/1/script.php