Windows: Can I set the folder in which iTunes backs up my iPhone

I have a Windows 10 PC with 2 hard drives.

  1. C: Smallest SSD on Windows and Office

  2. RE: large SATA (2TB) that stores all my data.

When iTunes backs up my iPhone on my PC, it defaults to C: under the Users folder. Is there a way to set it up to make backups somewhere on my RE: drive? I do not see any options there. j & # 39; I RE: set for my library, but I know it's different. I agree to manually configure the registry if necessary, but hopefully a more legitimate route in case I need a restoration later.